When Every Fever Raised a Question, Expertise Brought the Answer
Mr. R Panchal, a 53-year-old gentleman, was admitted to Marengo CIMS Hospital after experiencing persistent high-grade fever, severe weakness, and growing uncertainty about his health. He had recently been treated at another hospital with multiple intravenous antibiotics, yet his fever kept returning. The absence of a clear diagnosis left him physically drained and emotionally distressed.
He came under the care of Dr. Surabhi Madan, Infectious Disease Specialist, who recognized early that this was not a routine infection. A detailed clinical evaluation revealed leukopenia, elevated inflammatory markers, and significant radiological changes—prompting a structured and methodical diagnostic approach. With timely multidisciplinary consultations and advanced investigations, including bone marrow biopsy, autoimmune profiling, and PET scan, the underlying cause was progressively uncovered.
The findings suggested a post-viral inflammatory syndrome within the adult-onset Still’s disease spectrum, along with early liver parenchymal involvement—explaining the persistence of symptoms despite prior treatment. Throughout his hospital stay, Dr. Surabhi Madan closely monitored his evolving clinical picture, dynamically adjusting therapy based on response and emerging evidence.
With targeted antibiotics, immunomodulatory therapy, and comprehensive supportive care, Mr. Panchal showed steady improvement. His fever subsided, blood parameters stabilized, and his strength gradually returned. By the time of discharge, he was hemodynamically stable, symptomatically improved, and reassured with a well-defined follow-up plan.
His recovery highlights the importance of clinical insight, perseverance, and coordinated care—reflecting Dr. Surabhi Madan’s extensive experience and expertise in Infectious Diseases, particularly in managing complex and challenging cases of Pyrexia of Unknown Origin (PUO).
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